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Drugging the NLRP3 inflammasome: from signalling mechanisms to therapeutic targets

Lieselotte Vande Walle, Mohamed Lamkanfi

2023Nature Reviews Drug Discovery293 citationsDOIOpen Access PDF

Topics & Concepts

InflammasomePyroptosisCaspase 1InflammationCell biologyInnate immune systemProgrammed cell deathBiologyImmune systemImmunologyApoptosisBiochemistryInflammasome and immune disordersAutoimmune and Inflammatory Disorders ResearchKawasaki Disease and Coronary Complications
Drugging the NLRP3 inflammasome: from signalling mechanisms to therapeutic targets | Litcius