Tezacaftor is a direct inhibitor of sphingolipid delta-4 desaturase enzyme (DEGS)
Dinu Zinovie Ciobanu, Nara Liessi, Valeria Tomati, Valeria Capurro, Sine Mandrup Bertozzi, Maria Summa, Rosalia Bertorelli, Nicoletta Loberto, Dorina Dobi, Massimo Aureli, Lucilla Nobbio, Tiziano Bandiera, Nicoletta Pedemonte, Rosaria Bassi, Andrea Armirotti
Topics & Concepts
SphingolipidMedicineEnzymeCystic fibrosisComputational biologyGeneticsBiochemistryInternal medicineBiologySphingolipid Metabolism and SignalingCystic Fibrosis Research AdvancesPharmacological Receptor Mechanisms and Effects