Calix[4]pyrrolato Stibenium: Lewis Superacidity by Antimony(III)‐Antimony(V) Electromerism
Marcel Schorpp, Ravi Yadav, Daniel Roth, Lutz Greb
Abstract
Lewis superacids enable the activation of highly inert substrates. However, the permanent presence of a Lewis superacidic center comes along with a constantly increased intolerance toward functional groups or ambient conditions. Herein, we describe a strategy to unleash Lewis superacidity by electromerism. Experimental and computational results indicate that coordinating a Lewis base to Δ-calix[4]pyrrolato-antimony(III) triggers a ligand redox-noninnocent coupled transfer into antimony(V)-state that exhibits Lewis superacidic features. Lewis acidity by electromerism establishes a concept of potential generality for powerful yet robust reagents and on-site substrate activation approaches.
Topics & Concepts
Lewis acids and basesAntimonyChemistryLewis lung carcinomaSubstrate (aquarium)ReagentRedoxInertLigand (biochemistry)Combinatorial chemistryOrganic chemistryCatalysisReceptorCancerMedicineOceanographyInternal medicineMetastasisBiochemistryGeologyOrganoboron and organosilicon chemistrySulfur-Based Synthesis TechniquesChemical Synthesis and Reactions