Cellulose‐enriched ascorbic acid for wound dressing application: Future medical textile
Afrinal Firmanda, Melbi Mahardika, Farah Fahma, Devita Amelia, Agus Wedi Pratama, Nanda Rizki Amalia, Edi Syafri, Mounir El Achaby
Abstract
Abstract Wounds infected by resistant microbes have become a cost and health problem worldwide. In modern wound care, healing mechanisms require particular strategies, such as adding natural antioxidants and antimicrobials in a biocompatible biopolymer matrix mimicking extracellular tissue such as cellulose. Here, ascorbic acid or Vitamin C is a promising bioactive as a topical drug loaded in a cellulose‐based composite matrix for skin tissue repair. Ascorbic acid, cellulose, or cellulose composites enriched with ascorbic acid have shown better biocompatibility and biological effects for accelerating wound healing, making them promising as sustainable medical textiles. Future challenges relate to the ideal engineered wound dressing design, raw material toxicity, and 3D printing technology.