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The protective effect of 7-hydroxycoumarin against cisplatin-induced liver injury is mediated via attenuation of oxidative stress and inflammation and upregulation of Nrf2/HO-1 pathway

Demiana H. Sami, Ayman S. Soliman, Akef A. Khowailed, Reem S. Alruhaimi, Emad H. M. Hassanein, Emadeldin M. Kamel, Ayman M. Mahmoud

2023Environmental Science and Pollution Research16 citationsDOI

Topics & Concepts

Oxidative stressMalondialdehydePharmacologyReactive oxygen speciesChemistryInflammationAntioxidantHeme oxygenaseAlkaline phosphataseBilirubinNitric oxide synthaseNitric oxideLiver injuryCisplatinInternal medicineBiochemistryMedicineHemeChemotherapyEnzymeOrganic chemistryChemotherapy-induced organ toxicity mitigationChemotherapy-induced cardiotoxicity and mitigationGenomics, phytochemicals, and oxidative stress
The protective effect of 7-hydroxycoumarin against cisplatin-induced liver injury is mediated via attenuation of oxidative stress and inflammation and upregulation of Nrf2/HO-1 pathway | Litcius