A Review of Chalcones: Synthesis, Reactions, and Biological Importance
Shorouk S. Mukhtar, Nesrin M. Morsy, Ashraf S. Hassan, Taghrid S. Hafez, Hamdi M. Hassaneen, Fatma M. Saleh
Abstract
Chalcones are considered an important scaffold in organic compounds. Many of their derivatives have a lot of applications. Therefore, this review was covered some synthesis methods of chalcones such as Claisen-Schmidt’s condensation, coupling reaction, continuous-flow deuteration reaction, and other reactions. Also, some reactions were discussed such as the synthesis of seven, six, and five-membered ring heterocyclic compounds. Moreover, some of their biological applications were mentioned like antimicrobial, anticancer, anti-inflammatory, antioxidants, and others with some details.
Topics & Concepts
ChemistryBiochemical engineeringCombinatorial chemistryEngineeringSynthesis and biological activitySynthesis and Characterization of Heterocyclic CompoundsSynthesis and Biological Evaluation