Litcius/Paper detail

Hematopoietic Progenitor Kinase1 (HPK1) Mediates T Cell Dysfunction and Is a Druggable Target for T Cell-Based Immunotherapies

Jingwen Si, Xiangjun Shi, Shuhao Sun, Bin Zou, Yaopeng Li, Dongjie An, Xingyu Lin, Yan Gao, Fei Long, Bo Pang, Xing Liu, Tian Liu, Wenna Chi, Ligong Chen, Dimiter S. Dimitrov, Yan Sun, Xinru Du, Wen Yin, Guangxun Gao, Junxia Min, Lai Wei, Xuebin Liao

2020Cancer Cell185 citationsDOIOpen Access PDF

Topics & Concepts

DruggabilityT cellBiologyCancer researchCellEffectorImmunotherapyImmune systemHaematopoiesisImmunologyCell biologyStem cellGeneticsGeneCAR-T cell therapy researchAdvancements in Semiconductor Devices and Circuit DesignProtein Degradation and Inhibitors