Complement factor I: Regulatory nexus, driver of immunopathology, and therapeutic
Thomas M Hallam, Stephen J. Sharp, Aikaterini Andreadi, David Kavanagh
Topics & Concepts
Complement systemComplement factor IImmunologyEculizumabHaploinsufficiencyFactor HAlternative complement pathwayComplement component 2Complement component 5NeopterinAtypical hemolytic uremic syndromePenetranceImmunopathologyBiologyMedicineGeneticsGeneAntibodyPhenotypeComplement system in diseasesRenal Diseases and Glomerulopathies