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Cognitive enhancement, TAU phosphorylation reduction, and neuronal protection by the treatment of an LRRK2 inhibitor in a tauopathy mouse model

Sara Castro‐Sánchez, Josefa Zaldívar-Díez, Enrique Luengo, Manuela G. López, Carmen Gil, Ana Martı́nez, Isabel Lastres‐Becker

2020Neurobiology of Aging20 citationsDOI

Topics & Concepts

TauopathyLRRK2NeuroprotectionKinasePhosphorylationSynaptic plasticityNeuroscienceCell biologyTau proteinHippocampusParkinson's diseaseCognitive declineBiologyPharmacologyChemistryNeurodegenerationMedicineBiochemistryAlzheimer's diseaseInternal medicineDiseaseDementiaReceptorParkinson's Disease Mechanisms and TreatmentsAlzheimer's disease research and treatmentsMedicinal Plants and Neuroprotection
Cognitive enhancement, TAU phosphorylation reduction, and neuronal protection by the treatment of an LRRK2 inhibitor in a tauopathy mouse model | Litcius