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Design, synthesis, in-silico and biological evaluation of novel 2-Amino-1,3,4-thiadiazole based hydrides as B-cell lymphoma-2 inhibitors with potential anticancer effects

Seham A. Ibrahim, Maha M. Salem, Hayam A. Abd Elsalam, Ahmed A. Noser

2022Journal of Molecular Structure28 citationsDOI

Topics & Concepts

ChemistryIn silicoSynthonCombinatorial chemistryLead compoundCancer cellStereochemistryIn vitroBiochemistryCancerMedicineGeneInternal medicineSynthesis and biological activitySynthesis and Biological EvaluationSynthesis and Characterization of Heterocyclic Compounds
Design, synthesis, in-silico and biological evaluation of novel 2-Amino-1,3,4-thiadiazole based hydrides as B-cell lymphoma-2 inhibitors with potential anticancer effects | Litcius