DNA-double strand breaks enhance the expression of major histocompatibility complex class II through the ATM-NF-κΒ-IRF1-CIITA pathway
Tsukasa Oda, Ruri Nakamura, Tetsuhiro Kasamatsu, Nanami Gotoh, Keiko Okuda, Takayuki Saitoh, Hiroshi Handa, Hirokazu Murakami, Takayuki Yamashita
Topics & Concepts
CIITAIRF1BiologyCell biologyMajor histocompatibility complexAntigen presentationCancer researchTranscription factorMHC class IIImmune systemT cellMolecular biologyImmunologyGeneticsGeneImmune Cell Function and InteractionDNA Repair MechanismsImmunotherapy and Immune Responses