Exosomal B7-H3 facilitates colorectal cancer angiogenesis and metastasis through AKT1/mTOR/VEGFA pathway
Rendi Wu, Yawen Zhang, Xinyi Xu, Qingjun You, Chunjing Yu, Weipeng Wang, Yong Mao
Topics & Concepts
AngiogenesisMetastasisCancer researchMicrovesiclesPI3K/AKT/mTOR pathwayAKT1Tumor microenvironmentTumor progressionBiologyVascular endothelial growth factor AProtein kinase BColorectal cancerSignal transductionCancerVascular endothelial growth factorImmunologyMedicineCell biologyInternal medicinemicroRNAVEGF receptorsBiochemistryGeneTumor cellsExtracellular vesicles in diseaseImmunotherapy and Immune ResponsesImmune Cell Function and Interaction