Litcius/Paper detail

N, S, Br co-doped carbon dots: One-step synthesis and fluorescent detection of 6-mercaptopurine in tablet

Qi Wang, Ying Cheng, Lifeng Ding, Shengling Li, Jie Zhang, Yulan Niu, Ziye Jing

2023Journal of Pharmaceutical Analysis15 citationsDOIOpen Access PDF

Abstract

Scheme of synthesis of N, S, Br-CDs and fluorescent detection of 6-MP. • A suitable detection method for 6-mercaptopurine (6-MP) was developed. • N, S, Br-carbon dots (N, S, Br-CDs) synthesized by one-step hydrothermal method. • The as-synthesized N, S, Br-CDs exhibited favorable fluorescence. • The fluorescence intensity of the N, S, Br-CDs was quenched by 6-MP. • The developed method is suitable for detecting 6-MP in real pharmaceutical samples.

Topics & Concepts

FluorescenceMercaptopurineCarbon fibersDopingChemistryNanotechnologyCombinatorial chemistryMaterials scienceOptoelectronicsPhysicsOpticsBiologyPharmacologyComposite numberComposite materialCarbon and Quantum Dots ApplicationsAdvanced biosensing and bioanalysis techniquesElectrochemical sensors and biosensors