Gold(I)‐<i>N</i>‐Heterocyclic Carbene Synthons in Organometallic Synthesis
Thomas Scattolin, Giovanni Tonon, Eleonora Botter, Sébastien G. Guillet, Nikolaos V. Tzouras, Steven P. Nolan
Abstract
The prominent role of gold-N-heterocyclic carbene (NHC) complexes in numerous research areas such as homogeneous (photo)catalysis, medicinal chemistry and materials science has prompted organometallic chemists to design gold-based synthons that permit access to target complexes through simple synthetic steps under mild conditions. In this review, the main gold-NHC synthons employed in organometallic synthesis are discussed. Mechanistic aspects involved in their synthesis and reactivity as well as applications of gold-NHC synthons as efficient pre-catalysts, antitumor agents and/or photo-emissive materials are presented.
Topics & Concepts
SynthonCarbeneOrganometallic chemistryCatalysisReactivity (psychology)ChemistryHomogeneousCombinatorial chemistryHomogeneous catalysisNanotechnologyGroup 2 organometallic chemistryOrganic chemistryMaterials scienceMoleculeMedicineThermodynamicsAlternative medicinePhysicsPathologyCatalytic Alkyne ReactionsN-Heterocyclic Carbenes in Organic and Inorganic ChemistryCatalytic Cross-Coupling Reactions