Litcius/Paper detail

Regulatory mechanisms of lipid biosynthesis in microalgae

Hui Chen, Qiang Wang

2021Biological reviews/Biological reviews of the Cambridge Philosophical Society183 citationsDOI

Abstract

Microalgal lipids are highly promising feedstocks for biofuel production. Microalgal lipids, especially triacylglycerol, and practical applications of these compounds have received increasing attention in recent years. For the commercial use of microalgal lipids to be feasible, many fundamental biological questions must be addressed based on detailed studies of algal biology, including how lipid biosynthesis occurs and is regulated. Here, we review the current understanding of microalgal lipid biosynthesis, with a focus on the underlying regulatory mechanisms. We also present possible solutions for overcoming various obstacles to understanding the basic biology of microalgal lipid biosynthesis and the practical application of microalgae-based lipids. This review will provide a theoretical reference for both algal researchers and decision makers regarding the future directions of microalgal research, particularly pertaining to microalgal-based lipid biosynthesis.

Topics & Concepts

BiosynthesisBiochemical engineeringBiologySynthetic biologyLipid metabolismLipid accumulationBiofuelProduction (economics)Computational biologyBiotechnologyBiochemistryEngineeringGeneMacroeconomicsEconomicsAlgal biology and biofuel productionPhotosynthetic Processes and MechanismsMicrobial Metabolic Engineering and Bioproduction