Theobromine mitigates IL-1β-induced oxidative stress, inflammatory response, and degradation of type II collagen in human chondrocytes
Ronghe Gu, Yu Shi, Weiguo Huang, Chendeng Lao, Zhuan Zou, Songmu Pan, Zonggui Huang, Zonggui Huang
Topics & Concepts
TheobromineChondrocyteChemistryTumor necrosis factor alphaOxidative stressCytokineReactive oxygen speciesPharmacologyImmunologyBiochemistryCell biologyMedicineBiologyTheophyllineIn vitroInflammatory mediators and NSAID effectsNatural product bioactivities and synthesisOsteoarthritis Treatment and Mechanisms