Recurrent <i>Clostridioides difficile</i> infection: Recognition, management, prevention
Constantine Tsigrelis
Abstract
infection (CDI) is the most common cause of diarrhea in hospitalized patients and results in substantial morbidity, mortality, and costs. Its clinical management, primarily with antibiotics, is often complicated by recurrent episodes. These recurrent CDI episodes are thought to be caused by antibiotic disruption of colonic microbiota and usually occur within 4 weeks of completing antibiotic therapy. The risk of recurrent CDI increases after the first episode, creating a need for management strategies to diagnose, treat, and prevent these complications.
Topics & Concepts
MedicineClostridioidesAntibioticsDiarrheaIntensive care medicineAntibiotic therapyAntibiotic-associated diarrheaInternal medicineClostridium difficilePediatricsMicrobiologyBiologyClostridium difficile and Clostridium perfringens researchMicroscopic ColitisGastrointestinal motility and disorders