Decline of Antibodies to Major Viral and Bacterial Respiratory Pathogens During the COVID-19 Pandemic
Natalie Lorenz, Alex James, Tiaan Van Rooyen, Aimee Paterson, Ciara Ramiah, Lauren H. Carlton, Prachi Sharma, Michael G. Baker, Richard Charlewood, Reuben McGregor, Nicole J. Moreland
Abstract
Surges in infections caused by respiratory pathogens have been documented in multiple settings after relaxation of pandemic restrictions. Antibodies to major antigens from respiratory syncytial virus and group A Streptococcus waned significantly in a longitudinal adult cohort throughout the pandemic. This waning may have contributed to the pathogen-surges that followed.
Topics & Concepts
PandemicVirologyRespiratory systemImmunologyAntibodyVirusPathogenCoronavirus disease 2019 (COVID-19)MedicineBiologyInternal medicineDiseaseInfectious disease (medical specialty)Respiratory viral infections researchRespiratory Support and MechanismsCOVID-19 Clinical Research Studies