Carboxymethyl Cellulose (CMC) as a Recyclable Green Catalyst Promoted Eco-Friendly Protocol for the Solvent-Free Synthesis of 1<i>H</i>-Pyrazolo[1,2-<i>b</i>]Phthalazine-5,10-Dione Derivatives
Farzaneh Mohamadpour
Abstract
An eco-safe synthetic route for convenient one-pot synthesizing 1H-pyrazolo[1,2-b] phthalazine-5,10-dione derivatives through Knoevenagel-Michael cyclocondensation is reported in carboxymethyl cellulose (CMC) based on green chemistry principles. The prominent benefits include use of recyclable green catalyst, commercially accessible inexpensive starting materials, operational simplicity, non-hazardous reaction circumstances, high atom-economy, solvent-free, short reaction times and high yields.
Topics & Concepts
ChemistryPhthalazineAtom economyGreen chemistryCatalysisKnoevenagel condensationCarboxymethyl celluloseEnvironmentally friendlyOrganic chemistryCombinatorial chemistryReaction mechanismEcologySodiumBiologyMulticomponent Synthesis of HeterocyclesSynthesis and biological activityChemistry and Chemical Engineering