Crystal structure of the periplasmic sensor domain of histidine kinase VbrK suggests indirect sensing of β-lactam antibiotics
Boon Chong Goh, Yong Kang Chua, Xinlei Qian, Jianqing Lin, Martin Savko, Peter C. Dedon, Julien Lescar
Topics & Concepts
Periplasmic spaceIsothermal titration calorimetryLactamHistidine kinaseChemistryAntibioticsBiophysicsBiochemistryBiologyGeneHistidineStereochemistryEnzymeEscherichia coliBacterial Genetics and BiotechnologyProtein Structure and DynamicsBacteriophages and microbial interactions