Robust differences in cortical cell type proportions across healthy human aging inferred through cross-dataset transcriptome analyses
Yuxiao Chen, Emma N Hunter, Keon Arbabi, Alexandre Guet-McCreight, Micaela Elisa Consens, Daniel Felsky, Etienne Sibille, Shreejoy J. Tripathy
Topics & Concepts
Cell typeBiologyNeuroscienceTranscriptomeMicrogliaCerebral cortexHuman brainAgeingAging brainBrain agingCellGene expressionCognitionGeneGeneticsImmunologyInflammationNeuroinflammation and Neurodegeneration MechanismsSingle-cell and spatial transcriptomicsImmune cells in cancer