Physiology of Left Ventricular Septal Pacing and Left Bundle Branch Pacing
Jesse Rijks, Justin Luermans, Luuk I.B. Heckman, Antonius van Stipdonk, Frits W. Prinzen, Joost Lumens, Kevin Vernooy
Abstract
Following the recognition of the adverse effects of right ventricular pacing, alternative permanent pacing strategies aiming to maintain a synchronous ventricular contraction have been sought. The quest for the optimal pacing site has recently led to several promising and rapidly emerging new pacing strategies, such as left ventricular septal pacing and left bundle branch pacing. In both animal and human studies, these pacing strategies seem to maintain electrical and mechanical activation of the left ventricle to a (near)physiologic level. However, more studies on the long-term effects of both strategies are needed.
Topics & Concepts
MedicineVentricleVentricular pacingCardiologyInternal medicineCardiac pacingLeft bundle branch blockHeart failureCardiac pacing and defibrillation studiesCardiac Structural Anomalies and RepairCardiac Arrhythmias and Treatments