Polystyrene nanoplastics induce cardiotoxicity by upregulating HIPK2 and activating the P53 and TGF-β1/Smad3 pathways
Jian-Zheng Yang, Kai-Kai Zhang, Clare Hsu, Lin Miao, Lijian Chen, Jiali Liu, Jia-Hao Li, Xiuwen Li, Jiahao Zeng, Long Chen, Jihui Li, Xiao‐Li Xie, Qi Wang
Topics & Concepts
CardiotoxicityPharmacologyDownregulation and upregulationIsoprenalineDoxorubicinApoptosisChemistryCardiac fibrosisTransforming growth factorFibrosisCancer researchToxicityMedicineInternal medicineStimulationBiochemistryChemotherapyGeneOrthopaedic implants and arthroplastyMesenchymal stem cell researchMicroplastics and Plastic Pollution