Inhalable liposomes for treating lung diseases: clinical development and challenges
Pranav Ponkshe, Sheng Feng, Chalet Tan
Abstract
Inhalation delivery of liposomal drugs has distinct advantages for the treatment of pulmonary diseases. Inhalable liposomes of several drugs are currently undergoing clinical trials for a range of indications in the lungs. Herein, general principles of pulmonary delivery as well as the clinical development of inhalable liposomal drugs are reviewed.
Topics & Concepts
LiposomeMedicineInhalationClinical trialIntensive care medicineDrug deliveryPharmacologyNanotechnologyPathologyMaterials scienceAnesthesiaInhalation and Respiratory Drug DeliveryAdvanced Drug Delivery SystemsDrug Solubulity and Delivery Systems