Dimethyl itaconate reprograms neurotoxic to neuroprotective primary astrocytes through the regulation of NLRP3 inflammasome and NRF2/HO-1 pathways
Mohammad Darvish Khadem, Mohammad Reza Tabandeh, Arvand Haschemi, Alireza Kheirollah, Ali Shahriari
Topics & Concepts
InflammasomeNeuroprotectionAstrocyteNeurotoxicitySuperoxide dismutaseBiologyMicrogliaCell biologyNeuroinflammationReactive oxygen speciesInflammationBiochemistryOxidative stressPharmacologyChemistryImmunologyNeuroscienceToxicityCentral nervous systemOrganic chemistryNeuroinflammation and Neurodegeneration MechanismsInflammasome and immune disordersAnesthesia and Neurotoxicity Research