Photocurable injectable Janus hydrogel with minimally invasive delivery for all-in-one treatment of gastric perforations and postoperative adhesions
Xiaoqi Wu, Zihan Wang, Jie Xu, Liu Yu, Maoyu Qin, Jianfeng Li, Sitian Liu, Weihan Zheng, Zeyu Li, Jun Ouyang, Yanbing Li, Guoxin Li, Ling Wang, Wenhua Huang, Yaobin Wu
Abstract
Our findings reveal that the injectable Janus hydrogel offers an all-in-one strategy for sutureless GP repair and concurrent prevention of postoperative adhesion formation by incorporating the MID device in minimally invasive surgery, presenting the significant potential to reduce patient surgical complications.
Topics & Concepts
Self-healing hydrogelsInvasive surgeryWound healingBiomedical engineeringMinimally invasive proceduresMedicineDeliverableAdhesionSurgeryTissue AdhesionMaterials scienceComposite materialEconomicsManagementPolymer chemistrySurgical Sutures and AdhesivesIntestinal and Peritoneal AdhesionsHemostasis and retained surgical items