Novel quinoxaline analogs as telomeric G-quadruplex ligands exert antitumor effects related to enhanced immunomodulation
Jiaxin Wang, Xiaodong Wang, Ming-Hao Hu
Topics & Concepts
ChemistryDNA damageTelomereCytotoxic T cellApoptosisQuinoxalineIn vivoCancer researchCell biologyDNACell cycle checkpointG-quadruplexIn vitroCancer cellCD8Cell cycleCancerImmune systemBiochemistryBiologyImmunologyGeneticsOrganic chemistryDNA and Nucleic Acid ChemistrySynthesis and Biological EvaluationRNA Interference and Gene Delivery