Mortalin depletion induces MEK/ERK-dependent and ANT/CypD-mediated death in vemurafenib-resistant B-RafV600E melanoma cells
Pui–Kei Wu, Seung‐Keun Hong, Jong‐In Park
Topics & Concepts
VemurafenibCancer researchMelanomaGene knockdownProgrammed cell deathSynthetic lethalityMAPK/ERK pathwayBiologyApoptosisMitochondrionMutantVoltage-dependent anion channelCell biologyKinaseGeneBiochemistryEscherichia coliMetastatic melanomaBacterial outer membraneMelanoma and MAPK PathwaysHeat shock proteins researchSignaling Pathways in Disease