H3K9 lactylation in malignant cells facilitates CD8+ T cell dysfunction and poor immunotherapy response
Ruijie Wang, Chuwen Li, Zhongyi Cheng, Mingyu Li, Jianbo Shi, Zhiyuan Zhang, Shufang Jin, Hailong Ma
Topics & Concepts
ImmunotherapyCD8Cytotoxic T cellCancer researchImmunologyT cellBiologyMedicineCell biologyImmune systemGeneticsIn vitroImmune cells in cancerCancer Immunotherapy and BiomarkersCancer, Stress, Anesthesia, and Immune Response