Elevated levels of active Transforming Growth Factor β1 in the subchondral bone relate spatially to cartilage loss and impaired bone quality in human knee osteoarthritis
Dzenita Muratovic, David M. Findlay, Ryan D. Quarrington, Xu Cao, Lucian B. Solomon, Gerald J. Atkins, J.S. Kuliwaba
Topics & Concepts
Subchondral boneOsteoarthritisArticular cartilageCartilageTransforming growth factorHuman boneMedicineAnatomyInternal medicinePathologyBiologyIn vitroAlternative medicineBiochemistryOsteoarthritis Treatment and MechanismsTGF-β signaling in diseasesConnective Tissue Growth Factor Research