Apoptotic activities of brusatol in human non-small cell lung cancer cells: Involvement of ROS-mediated mitochondrial-dependent pathway and inhibition of Nrf2-mediated antioxidant response
Jianhui Xie, Zhengquan Lai, Xinghan Zheng, Huijun Liao, Yan‐Fang Xian, Qian Li, Jingjing Wu, Siu‐Po Ip, Youliang Xie, Jiannan Chen, Ziren Su, Zhi‐Xiu Lin, Xiaobo Yang
Topics & Concepts
ApoptosisReactive oxygen speciesA549 cellPharmacologyChemistryCancer cellCell growthGrowth inhibitionCell cultureCell cycle checkpointBiologyCell cycleBiochemistryCancerGeneticsPhytochemical compounds biological activitiesGenomics, phytochemicals, and oxidative stressCancer Mechanisms and Therapy