RIPK1 inhibitors: A key to unlocking the potential of necroptosis in drug development
Yinliang Bai, Yujun Qiao, Mingming Li, Wenzhen Yang, Haile Chen, Yanqing Wu, Honghua Zhang
Topics & Concepts
NecroptosisRIPK1Drug discoveryProgrammed cell deathDrug repositioningChemistryPharmacologyDrugApoptosisBiologyBiochemistryCell death mechanisms and regulationPARP inhibition in cancer therapyinterferon and immune responses