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Association of Impaired Spermatogenesis With the Use of Immune Checkpoint Inhibitors in Patients With Metastatic Melanoma

Jason M. Scovell, Karl Benz, Iryna Samarska, Taylor P. Kohn, Jody E. Hooper, Andrés Matoso, Amin S. Herati

2020JAMA Oncology56 citationsDOIOpen Access PDF

Abstract

This cohort study examines the potential association of the use of immune checkpoint inhibitors with testicular histopathologic conditions.

Topics & Concepts

MedicineMelanomaMetastatic melanomaImmune checkpointOncologyInternal medicineIpilimumabCancer researchImmune systemImmunotherapyPharmacologyCancerImmunologyImmunotherapy and Immune ResponsesPARP inhibition in cancer therapyReproductive Biology and Fertility
Association of Impaired Spermatogenesis With the Use of Immune Checkpoint Inhibitors in Patients With Metastatic Melanoma | Litcius