Tumor-associated macrophages expressing the transcription factor IRF8 promote T cell exhaustion in cancer
Briana G. Nixon, Fengshen Kuo, Liangliang Ji, Ming Liu, Kristelle J. Capistrano, Mytrang Do, Ruth A. Franklin, Xiaodi Wu, Emily R. Kansler, Raghvendra M. Srivastava, Tanaya A. Purohit, Alejandro Sánchez, Lynda Vuong, Chirag Krishna, Xinxin Wang, Herbert C. Morse, James J. Hsieh, Timothy A. Chan, Kenneth M. Murphy, James J. Moon, A. Ari Hakimi, Ming O. Li
Topics & Concepts
IRF8CTL*Cytotoxic T cellBiologyPriming (agriculture)ImmunologyCancer researchTumor-associated macrophageTranscription factorImmune systemDendritic cellTumor microenvironmentCD8GeneGerminationBiochemistryBotanyIn vitroImmune cells in cancerImmune Cell Function and InteractionImmunotherapy and Immune Responses