The CD8+ T cell tolerance checkpoint triggers a distinct differentiation state defined by protein translation defects
Willem Van Der Byl, Simone Nüssing, Timothy J. Peters, Antonio Ahn, Hanjie Li, Guy Ledergor, Eyal David, Andrew S. Koh, Mayura V. Wagle, Christian Deo T. Deguit, Maria N. de Menezes, Avraham Travers, Shienny Sampurno, Kelly M. Ramsbottom, Rui Li, Axel Kallies, Paul A. Beavis, Ralf Jungmann, Maartje M. C. Bastings, Gabrielle T. Belz, Shom Goel, Joseph A. Trapani, Gerald R. Crabtree, Howard Y. Chang, Ido Amit, Christopher C. Goodnow, Fabio Luciani, Ian A. Parish
Topics & Concepts
BiologyTranslation (biology)Cell biologyCD8Cytotoxic T cellComputational biologyCancer researchGeneticsAntigenGeneMessenger RNAIn vitroImmune Cell Function and InteractionCAR-T cell therapy researchT-cell and B-cell Immunology