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Novel thienopyrimidine-aminothiazole hybrids: Design, synthesis, antimicrobial screening, anticancer activity, effects on cell cycle profile, caspase-3 mediated apoptosis and VEGFR-2 inhibition

Yara El‐Dash, Emad M. Elzayat, Amr M. Abdou, Rasha A. Hassan

2021Bioorganic Chemistry62 citationsDOI

Topics & Concepts

ChemistrySorafenibCandida albicansApoptosisCell cultureCell cycle checkpointCell growthCytotoxic T cellGrowth inhibitionCell cyclePharmacologyBiochemistryCancer researchBiologyMicrobiologyIn vitroGeneticsHepatocellular carcinomaSynthesis and biological activityBioactive Compounds and Antitumor AgentsMulticomponent Synthesis of Heterocycles
Novel thienopyrimidine-aminothiazole hybrids: Design, synthesis, antimicrobial screening, anticancer activity, effects on cell cycle profile, caspase-3 mediated apoptosis and VEGFR-2 inhibition | Litcius