GTM-3, an Extra-Large Pore Enantioselective Chiral Zeolitic Catalyst
Ramón de la Serna, David Nieto, Raquel Sainz, Beatriz Bernardo‐Maestro, Álvaro Mayoral, Carlos Márquez‐Álvarez, Joaquín Pérez‐Pariente, Luis Gómez‐Hortigüela
Abstract
-stilbene oxide with alcohols, yielding unprecedented product enantiomeric excesses up to 30%. Our discovery opens the way for the use of accessible chiral zeolitic materials for the catalytic asymmetric synthesis of chiral pharmaceutical compounds.
Topics & Concepts
Enantiopure drugEnantioselective synthesisChemistryEnantiomerCatalysisEpoxideCombinatorial chemistryOrganic chemistryOxideEnantiomeric excessZeolite Catalysis and SynthesisMesoporous Materials and CatalysisMetal-Organic Frameworks: Synthesis and Applications