Litcius/Paper detail

Cross-Comparison of Human iPSC Motor Neuron Models of Familial and Sporadic ALS Reveals Early and Convergent Transcriptomic Disease Signatures

Ritchie Ho, Michael J. Workman, Pranav Mathkar, Kathryn Wu, Kevin J. Kim, Jacqueline G. O’Rourke, M Kellogg, Valérie Montel, Maria G. Bañuelos, Olubankole Aladesuyi Arogundade, Sandra Díaz-García, Daniel Oheb, Steven K. Huang, Irina Khrebtukova, Lisa Watson, John Ravits, Kevin Taylor, Robert H. Baloh, Clive N. Svendsen

2020Cell Systems48 citationsDOIOpen Access PDF

Topics & Concepts

BiologyAmyotrophic lateral sclerosisInduced pluripotent stem cellHox geneTranscriptomePhenotypeGeneticsComputational biologyDiseaseMotor neuronGeneNeuroscienceGene expressionEmbryonic stem cellPathologyMedicineSpinal cordAmyotrophic Lateral Sclerosis ResearchPluripotent Stem Cells ResearchSingle-cell and spatial transcriptomics