Structure-activity relationships in a series of auranofin analogues showing remarkable antiproliferative properties
Ida Landini, Lara Massai, Damiano Cirri, Tania Gamberi, Paolo Paoli, Luigi Messori, Enrico Mini, Stefania Nobili
Topics & Concepts
AuranofinChemistryThioredoxin reductaseGold CompoundsCytotoxicityCisplatinStereochemistryMetalCombinatorial chemistryBiochemistryIn vitroThioredoxinEnzymeOrganic chemistryInternal medicineRheumatoid arthritisMedicineChemotherapySurgeryMetal complexes synthesis and propertiesFerrocene Chemistry and ApplicationsRedox biology and oxidative stress