Human skin-resident CD8+ T cells require RUNX2 and RUNX3 for induction of cytotoxicity and expression of the integrin CD49a
Béatrice Zitti, Elena Hoffer, Wenning Zheng, Ram Vinay Pandey, Heinrich Schlums, Giovanna Perinetti Casoni, Irene Fusi, Lien Nguyen, Jaanika Kärner, Efthymia Kokkinou, Anna Carrasco, Jessica Gahm, Marcus Ehrström, Staffan Happaniemi, Åsa V. Keita, Charlotte Hedin, Jenny Mjösberg, Liv Eidsmo, Yenan T. Bryceson
Topics & Concepts
Cytotoxic T cellBiologyImmunosurveillanceCD8Cell biologyJurkat cellsImmunologyMolecular biologyCancer researchT cellIn vitroImmune systemGeneticsT-cell and B-cell ImmunologyImmune Cell Function and InteractionImmunotherapy and Immune Responses