Generation of hypoimmunogenic T cells from genetically engineered allogeneic human induced pluripotent stem cells
Bo Wang, Shoichi Iriguchi, Masazumi Waseda, Norihiro Ueda, Tatsuki Ueda, Huaigeng Xu, Atsutaka Minagawa, Akihiro Ishikawa, Hisashi Yano, Tomoko Ishi, Ryoji Ito, Motohito Goto, Riichi Takahashi, Yasushi Uemura, Akitsu Hotta, Shin Kaneko
Topics & Concepts
Cytotoxic T cellInduced pluripotent stem cellBiologyNatural killer T cellMajor histocompatibility complexIL-2 receptorCD8AntigenInterleukin 21MHC class IImmune systemAntigen-presenting cellImmunologyNK-92Stem cellCancer researchCell biologyT cellEmbryonic stem cellIn vitroBiochemistryGeneCAR-T cell therapy researchCRISPR and Genetic EngineeringImmune Cell Function and Interaction