Litcius/Paper detail

Discovery and biological evaluation of 6-aryl-4-(3,4,5-trimethoxyphenyl)quinoline derivatives with promising antitumor activities as novel colchicine-binding site inhibitors

Qianqian Xu, Yuxuan Tu, Yujing Zhang, Yutao Xiu, Zongjiang Yu, Hongfei Jiang, Chao Wang

2024European Journal of Medicinal Chemistry13 citationsDOI

Topics & Concepts

ChemistryQuinolineColchicineArylCombinatorial chemistryDrug discoveryBinding sitePharmacologyStereochemistryBiochemistryOrganic chemistryMedicineAlkylInternal medicineSynthesis and biological activitySynthesis and Biological EvaluationSynthesis of heterocyclic compounds
Discovery and biological evaluation of 6-aryl-4-(3,4,5-trimethoxyphenyl)quinoline derivatives with promising antitumor activities as novel colchicine-binding site inhibitors | Litcius