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A terminal α3-galactose modification regulates an E3 ubiquitin ligase subunit in Toxoplasma gondii

Msano Mandalasi, Hyun W. Kim, David F. Thieker, M. Osman Sheikh, Elisabet Gas‐Pascual, Kazi Rahman, Peng Zhao, Nitin G. Daniel, Hanke van der Wel, H. Travis Ichikawa, John Glushka, Lance Wells, Robert J. Woods, Zachary A. Wood, Christopher M. West

2020Journal of Biological Chemistry19 citationsDOIOpen Access PDF

Abstract

is a remarkable case of convergent evolution, which emphasizes the importance of the terminal α-galactose and establishes the phylogenetic breadth of Skp1 glycoregulation.

Topics & Concepts

Skp1BiochemistryBiologyPhosphofructokinase 2GlycanUbiquitin ligaseGlycosyltransferaseProtein subunitEnzymeUbiquitinGeneGlycoproteinToxoplasma gondii Research StudiesUbiquitin and proteasome pathwaysCarbohydrate Chemistry and Synthesis
A terminal α3-galactose modification regulates an E3 ubiquitin ligase subunit in Toxoplasma gondii | Litcius