Biocompatible Magnetic Conjugated Polymer Nanoparticles for Optical and Lifetime Imaging Applications in the First Biological Window
Struan Bourke, Federico Donà, Yurema Teijeiro Gonzalez, Basma Qazi Chaudhry, Maryna Panamarova, Eirinn Mackay, Peter S. Zammit, Lea Ann Dailey, Ulrike Eggert, Klaus Suhling, Mark Green
Abstract
-maleic anhydride) (PSMA) micelles. The resulting particles exhibited an emission peak at 657 nm, a fluorescence quantum yield of 21%, an average diameter of 65 nm, and a ζ potential of -30 mV. They are taken up by cells, and we describe their use in fluorescence microscopy of living Hela cells and zebrafish embryos and their associated cytotoxicity in HEK, HeLa, and HCE cells.
Topics & Concepts
Conjugated systemPolymerMaterials scienceHeLaFluorescenceQuantum yieldNanoparticleFluorescence microscopeIron oxide nanoparticlesPhotochemistrySuperparamagnetismNanotechnologyPolymer chemistryChemistryOpticsMagnetizationComposite materialBiochemistryCellPhysicsQuantum mechanicsMagnetic fieldLuminescence and Fluorescent MaterialsConducting polymers and applicationsSupramolecular Self-Assembly in Materials