High-concentrate diet elevates histone lactylation mediated by p300/CBP through the upregulation of lactic acid and induces an inflammatory response in mammary gland of dairy cows
Lairong Wang, Yan Wang, Meijuan Meng, Nana Ma, Guozhen Wei, Ran Huo, Guangjun Chang, Xiangzhen Shen
Topics & Concepts
Mammary glandLactationEndocrinologyInternal medicineTLR4InflammationProinflammatory cytokineBiologyDownregulation and upregulationLactic acidChemistryBiochemistryMedicinePregnancyGeneCancerBacteriaGeneticsBreast cancerRuminant Nutrition and Digestive PhysiologyReproductive Physiology in LivestockMilk Quality and Mastitis in Dairy Cows