Targeting SARS-CoV-2 Nsp12/Nsp8 interaction interface with approved and investigational drugs: an <i>in silico</i> structure-based approach
Özal Mutlu, Osman Mutluhan Uğurel, Emrah Sarıyer, Oğuz Ata, Tuğba Gül Inci, Erennur Ugurel, Sinem Koçer, Dilek Turgut‐Balik
Abstract
studies towards the treatment of COVID-19.Communicated by Ramaswamy H. Sarma.
Topics & Concepts
In silicoLigand (biochemistry)MutantChemistryBiochemistryBiophysicsBiologyReceptorGeneSARS-CoV-2 and COVID-19 ResearchComputational Drug Discovery MethodsRNA and protein synthesis mechanisms