Precision analysis of mutant U2AF1 activity reveals deployment of stress granules in myeloid malignancies
Giulia Biancon, Poorval Joshi, Joshua T. Zimmer, Torben Hunck, Yimeng Gao, Mark D. Lessard, Edward Courchaine, Andrew E. S. Barentine, Martin Machyna, Valentina Botti, Ashley Qin, Rana Gbyli, Amisha Patel, Yuanbin Song, Lea Kiefer, Gabriella Viero, Nils Neuenkirchen, Haifan Lin, Joerg Bewersdorf, Matthew D. Simon, Karla M. Neugebauer, Toma Tebaldi, Stephanie Halene
Topics & Concepts
BiologyMutantMyeloidCancer researchMyeloid cellsCell biologyComputational biologyGeneticsGeneRNA Research and SplicingAcute Myeloid Leukemia ResearchRNA modifications and cancer