Increasing trans-cleavage catalytic efficiency of Cas12a and Cas13a with chemical enhancers: Application to amplified nucleic acid detection
Fei Deng, Yi Li, Bitong Li, Ewa M. Goldys
Topics & Concepts
Cleavage (geology)ChemistryFörster resonance energy transferCRISPRNucleic acidCombinatorial chemistryDNAIntramolecular forceBiosensorEnhancerRNAFluorescenceBiophysicsBiochemistryStereochemistryGeneBiologyPaleontologyPhysicsFracture (geology)Gene expressionQuantum mechanicsCRISPR and Genetic EngineeringAdvanced biosensing and bioanalysis techniquesInnovation and Socioeconomic Development