LncRNA H19 downregulation confers erlotinib resistance through upregulation of PKM2 and phosphorylation of AKT in EGFR-mutant lung cancers
Chen Chen, Wei-Ran Liu, Bin Zhang, Lian-Min Zhang, Chenguang Li, Chang Liu, Hua Zhang, Yansong Huo, Yu-Chen Ma, Pengfei Tian, Qi Qi, Jingjing Li, Zhe Tang, Zhen-Fa Zhang, Giuseppe Giaccone, Dongsheng Yue, Changli Wang
Topics & Concepts
ErlotinibDownregulation and upregulationCancer researchProtein kinase BErlotinib HydrochlorideLung cancerMedicinePhosphorylationCancerBiologyEpidermal growth factor receptorPharmacologyInternal medicineCell biologyBiochemistryGeneCancer-related molecular mechanisms researchLung Cancer Treatments and MutationsMycobacterium research and diagnosis