Chemical Composition and antibacterial activity of hexane extract of Lycoperdon Pyriforme
Fariba Asgharpour, Ali Akbar Moghadamnia, Yasaman Alizadeh, Sohrab Kazemi
Abstract
Mushrooms contain active ingredients with their own antibacterial propFerties, so they can be used for prevention or treatment of high-risk diseases as well as chronic infections through extracting and optimizing these ingredients as biological and antibacterial substances. In this research, the aerial parts of the fungus, Lycoperdon pyriforme (L. pyriforme) species, was extracted via hexane solvent and then analyzed using GC/MS. The antibacterial test was also performed employing DD, MIC, and MBC methods on Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, and Bacillus subtilis strains. Following the analysis of L. pyriforme; Ergosta-5,7-dien-3-ol and 7,22-Ergostadienone compounds were obtained with values of 26.6% and 9.8%; respectively. This extract was only effective on S. aureus in a concentration of 125μg/ml. The results of this study demonstrated that the hexane extract of L. pyriforme could have antibacterial properties and also used as a natural antibiotic source for disinfection and treatment of infectious diseases.